This is intended as a support document for the Home Cure article on Cinnamon and Honey.
Honey as antibacterial
Most micro-organisms do not grow in honey because of its low water activity of 0.6.
(1)
http://en.wikipedia.org/wiki/Honey#cite_note-Prescott_1999-3
One precaution:
However, honey sometimes contains dormant endospores of the bacterium Clostridium botulinum, which can be dangerous to infants as the endospores can transform into toxin-producing bacteria in the infant’s immature intestinal tract, leading to illness and even death
Honey is mostly sugars and is not a significant source of vitamins or minerals.
Honey also contains tiny amounts of several compounds thought to function as antioxidants, including chrysin, pinobanksin, vitamin C, catalase, and pinocembrin.
Honey intoxication is more likely when using “natural” unprocessed honey and honey from farmers who may have a small number of hives.
Commercial processing, with pooling of honey from numerous sources generally dilutes any toxins.
When used topically (as, for example, a wound dressing), hydrogen peroxide is produced by dilution with body fluids. As a result, hydrogen peroxide is released slowly and acts as an antiseptic.
Hydrogen peroxide in honey is activated by dilution. However, unlike medical hydrogen peroxide, commonly 3% by volume, it is present in a concentration of only 1 mmol/L in honey.
Honey chelates and deactivates the free ion, which starts the formation of oxygen free radicals produced by hydrogen peroxide and the antioxidant constituents in honey help clean up oxygen free radicals present.
(2)
http://www.worldwidewounds.com/2001/november/Molan/honey-as-topical-agent.html
Diabetic ulcers
Topical honey has been used successfully in a comprehensive treatment of diabetic ulcers when the patient cannot use other topical antibiotics.
Acidity
The pH of honey is commonly between 3.2 and 4.5. This relatively acidic pH level prevents the growth of many bacteria.
(3)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297205/
J R Soc Med. 1999 June; 92(6): 283–285.
Antibacterial activity of honey against strains of Staphylococcus aureus from infected wounds.
R A Cooper, P C Molan, and K G Harding
School of Biomedical Sciences, University of Wales Institute, Cardiff, UK.
See letter “Manuka honey against Helicobacter pylori.”
See letter “Honey: is it worth rubbing it in?”
Abstract
The antibacterial action of honey in infected wounds does not depend wholly on its high osmolarity.
We tested the sensitivity of 58 strains of coagulase-positive Staphylococcus aureus, isolated from infected wounds, to a pasture honey and a manuka honey.
There was little variation between the isolates in their sensitivity to honey: minimum inhibitory concentrations were all between 2 and 3% (v/v) for the manuka honey and between 3 and 4% for the pasture honey.
Thus, these honeys would prevent growth of S. aureus if diluted by body fluids a further seven-fold to fourteen-fold beyond the point where their osmolarity ceased to be completely inhibitory.
The antibacterial action of the pasture honey relied on release of hydrogen peroxide, which in vivo might be reduced by catalase activity in tissues or blood.
The action of manuka honey stems partly from a phytochemical component, so this type of honey might be more effective in vivo. Comparative clinical trials with standardized honeys are needed.
(4)
http://www.medscape.com/viewarticle/565016
The clinical use of honey has received increasing interest in recent years, particularly its use as a topical antibacterial dressing.
Results thus far are extremely encouraging, and demonstrate that honey is effective against a broad range of microorganisms, including multiresistant strains.
This in-vitro study complements the work of others and focuses on the impact that a standardized honey can have on multiresistant bacteria that are regularly found in wounds and are responsible for increased morbidity.
Medihoney™ Antibacterial Honey (Medihoney™ Pty LTD, Richlands, Australia) is a standardized medical honey that is available in many countries including Australia, United Kingdom, Finland, Germany, Austria, and Turkey.
It is selected for its antibacterial activity and predominantly sourced from Leptospermum species.
Sterility of products is validated against international standards and products are manufactured to meet international quality system requirements.
The antibacterial activity of Medihoney is validated for the shelf life of the product, complying with the European Medical Device Directive.
The Maori (Polynesian settlers of New Zealand) vernacular name for Leptospermum honey is manuka, the name by which it is more popularly known.
Cinnamon: antibacterial
http://www.herbalsafety.utep.edu/herbs-pdfs/cinnamon.pdf
http://www.biomedcentral.com/1472-6882/6/39
Cinnamon, clove and lime oils were found to be inhibiting both gram-positive and gram-negative bacteria. Cinnamon oil can be a good source of antibacterial agents.
Cinnamon – anti-inflammatory
(1)
http://www.medicalnewstoday.com/articles/41026.php
Two studies presented at Experimental Biology 2006 provide new evidence for the beneficial effects (and biochemical actions) of cinnamon as an anti-inflammatory agent, and support earlier findings of its power as an anti-oxidant agent and an agent able to lower cholesterol, triglycerides, and glucose, and improve how well insulin functions.
In a related study, extracts of cloves also were found to improve the function of insulin and to lower glucose, total cholesterol, LDL and triglycerides in people with type 2 diabetes.
Earlier studies had shown these positive effects in laboratory studies; the study presented at Experimental Biology provides the first evidence of these beneficial effects in humans taking the equivalent of one to two cloves per day.
Earlier studies in the laboratory of one of the co-authors of all these papers, Dr. Richard A. Anderson, Beltsville Human Nutrition Research Center, United States Department of Agriculture, had shown that the equivalent of a quarter to half a teaspoon of cinnamon given to humans twice a day decreased risk factors for diabetes and cardiovascular disease, including glucose, cholesterol and triglycerides, by 10 to 30 percent.
These new studies showing cinnamon’s ability to block inflammation extend our understanding of the potential for the spice, says Dr. Anderson.
As an anti-inflammatory agent, cinnamon may be useful in preventing or mitigating arthritis as well as cardiovascular disease.
And as scientists increasingly understand the relationship between inflammation and insulin function in Alzheimer’s (causing some to refer to the neurodegenerative disease as “type 3 diabetes”), cinnamon’s ability to block inflammation and enhance insulin function may make it useful in combating that disease as well.
(2) Cinnamon
http://www.uspharmacist.com/content/t/complementary_and_alternative_medicine/c/10188/
Uses and Pharmacological Effects
Antimicrobial: Historically, cinnamon had been used to combat gastrointestinal disorders such as diarrhea, dyspepsia, and Helicobacter pylori (H pylori).
The antimicrobial effect of cinnamon was identified in a laboratory experiment in which pure Cinnamomum cassia extract, mainly composed of the active ingredient cinnamaldehyde, was tested on isolated strains of bacteria, including gram-positive Staphylococcus aurus, gram-negative Escherichia coli, Enterobacter aerogenes, Proteus vulgaris, Pseudomonas aeruginosa, Vibrio cholerae, Vibrio parahaemolyticuas , and Samonella typhymurium.
The antimicrobial effect resulted in a minimum inhibition concentration (MIC) of cinnamomum cassia extract ranging from 75 mcg/mL to 600 mcg/mL on these various bacteria.
However, conflicting data was obtained in a randomized, controlled pilot clinical trial of 15 patients ages 16 to 79 who had a positive Campylobacter urease test for H pylori.
Each patient in the control group received 40 mg of ethanol extract of cinnamon twice daily for four weeks; the control group received plain 95% ethanol.
With urea breath tests as the measurement of efficacy, the mean urea breath test before and after the study for the treated group were 22.1 and 24.4, respectively; the mean urea breath test before and after the study for the controlled group were 23.9 and 25.9, respectively.
This conclusive study found that 40 mg of cinnamon extract given twice daily was ineffective in eradicating H pylori.
Anti-inflammatory:
Although cinnamon historically had not been used to treat inflammatory disorders, its anti-inflammatory effect was demonstrated experimentally.
Specifically, Cinnamomum cassia was used to investigate the anti-inflammatory effect on nitric oxide (NO) and Nuclear factor kappa-b (NF-kB).
Both substances have been implicated in inflammation.
In acute and chronic inflammation, there is an increased production of NO, which promotes vasodilatation and results in increased vascular permeability and edema.
Nitric oxide also activates COX-2 enzyme involving in the biosynthetic pathway of inflammatory prostaglandins.2,6 NF-kB contributes to inflammation through induction of transcription of genes coding for inflammatory mediators.
It was found that cinnamaldehyde, specifically 2′-hydroxycinnamaldehyde found in Cinnamomum cassia extract, exhibited a dose-dependent inhibitory effect on NO production and transcriptional activity of NF-kB, thereby contributing to its anti-inflammatory qualities.
Antifungal:
Cinnamon oil has been reported as an antifungal agent, although current efficacy of cinnamon oil’s fungicidal effect has not been tested in clinical trials.
Experimentally, promising results on its antifungal activity were reported in two in vitro studies of cinnamon oil on Cryptococcus neoformans and Aspergillus niger.
Crytococcus neoformans is an opportunistic fungal pathogen affecting the lungs or meninges of immunocompromised or AIDS patients, causing pulmonary cryptococcosis or cryptococcocal meningitis.
It was found that the phenolic compound in cinnamon oil identified as eugenol is responsible for its fungitoxic activity.
Cinnamon oil’s antifungal property was again demonstrated in a more recent in vitro study on Aspergillus niger (A. niger), an opportunistic fungal pathogen residing in the air and, through inhalation of Aspergillus sp. spores, entering the respiratory tract of patients with AIDS or with immunocrompromised conditions to cause Aspergillosis.
Seventy-five botanical essential oils, including Cinnamomum zeylanicum and Cinnamomum cassia, were tested for the inhibition of hyphal growth and spore formation on inoculated agar with A. niger incubated at 28C for 48 hours.
Among the 75 botanical essential oils used, Cinnamomum zeylanicum and Cinnamomum cassia demonstrated maximal and superior results; the zone of hyphal growth inhibition and zone of spore formation were 43 and 40 versus 50 and 45 for Cinnamomum zeylanicum and Cinnamomum cassia, respectively.
Antioxidant:
There is more to cinnamon besides the antimicrobial, anti-inflammatory, and antifungal effects attributed to cinnamaldehyde found in Cinnamomum cassia powder and oil.
The presence of oligomeric proanthocyanidins (OPC), a class of bioflavonoid, opened a new area of research on its antioxidative effect. Through agriculture research, type A and type B oligomeric proanthocyanidins were identified in cinnamon spice via mass spectrometer analysis.
Additionally, it was found that over 84% to 90% of OPC found in cinnamon spice were type A OPC.
However, there has not been a specific study on the antioxidative effect of cinnamon alone.
Antioxidants are essential to the human body to neutralize free-reactive oxygen species, also known as free radicals, to maintain functional cellular membrane and structure.
Furthermore, free radicals associated with impaired glucose metabolism and antioxidants have been implicated in the regression of diabetes mellitus.
Honey
Honey is the only food on the planet that will not spoil or rot.
It will do what some call turning to sugar. In reality honey is always honey.
However, when left in a cool dark place for a long time it will do what I rather call “crystallizing”.
When this happens I loosen the lid, boil some water, and sit the honey container in the hot water, off the heat and let it liquefy It is then as good as it ever was.
Never boil honey or put it in a microwave. To do so will kill the enzymes in the honey.
Honey and Cinnamon:
It is found that a mixture of honey and Cinnamon cures most diseases.
Honey is produced in most of the countries of the world.
Scientists of today also accept honey as a ‘Ram Ban’ (very effective) medicine for all kinds of diseases.
Honey can be used without any side effects for any kind of diseases.Today’s science says that even though honey is sweet, if taken in the right dosage as a medicine, it does not harm diabetic patients.
Weekly World News, a magazine in Canada , in its issue dated 17 January,1995 has given the following list of diseases that can be cured by honey and cinnamon as researched by western scientists:
HEART DISEASES:
Make a paste of honey and cinnamon powder, apply on bread, instead of jelly and jam, and eat it regularly for breakfast.
It reduces the cholesterol in the arteries and saves the patient from heart attack.
Also, those who have already had an attack, if they do this process daily, they are kept miles away from the next attack.
Regular use of the above process relieves loss of breath and strengthens the heart beat.
In America and Canada , various nursing homes have treated patients successfully and have found that as you age, the arteries and veins lose their flexibility and get clogged; honey and cinnamon revitalize the arteries and veins.
ARTHRITIS:
Arthritis patients may take daily, morning and night, one cup of hot water with two spoons of honey and one small teaspoon of cinnamon powder.
If taken regularly even chronic arthritis can be cured.
**if it is osteoarthritis, it cannot be cured, because the bone is gone. However, it may help with inflammation.In a recent research conducted at the Copenhagen University , it was found that when the doctors treated their patients with a mixture of one tablespoon Honey and half teaspoon Cinnamon powder before breakfast, they found that within a week, out of the 200 people so treated, practically 73 patients were totally relieved of pain, and within a month, mostly all the patients who could not walk or move around because of arthritis started walking without pain.
BLADDER INFECTIONS:
Take two tablespoons of cinnamon powder and one teaspoon of honey in a glass of lukewarm water and drink it. It destroys the germs in the bladder…
CHOLESTEROL:
Two tablespoons of honey and three teaspoons of Cinnamon Powder mixed in 16 ounces of tea water, given to a cholesterol patient, was found to reduce the level of cholesterol in the blood by 10 percent within two hours.
As mentioned for arthritic patients, if taken three times a day, any chronic cholesterol is cured. According to information received in the said Journal, pure honey taken with food daily relieves complaints of cholesterol.
COLDS:
Those suffering from common or severe colds should take one tablespoon lukewarm honey with 1/4 spoon cinnamon powder daily for three days.
This process will cure most chronic cough, cold, and clear the sinuses.
UPSET STOMACH:
Honey taken with cinnamon powder cures stomach ache and also clears stomach ulcers from the root…
GAS:
According to the studies done in India and Japan , it is revealed that if Honey is taken with cinnamon powder the stomach is relieved of gas.
IMMUNE SYSTEM:
Daily use of honey and cinnamon powder strengthens the immune system and protects the body from bacteria and viral attacks. Scientists have found that honey has various vitamins and iron in large amounts.
Constant use of Honey strengthens the white blood corpuscles to fight bacterial and viral diseases.
INDIGESTION:
Cinnamon powder sprinkled on two tablespoons of honey taken before food relieves acidity and digests the heaviest of meals.
INFLUENZA:
A scientist in Spain has proved that honey contains a natural ‘ Ingredient’ which kills the influenza germs and saves the patient from flu.
LONGEVITY:
Tea made with honey and cinnamon powder, when taken regularly, arrests the ravages of old age.
Take four spoons of honey, one spoon of cinnamon
powder, and three cups of water and boil to make like tea.
Drink 1/4 cup, three to four times a day. It keeps the skin fresh and soft and arrests old age.
Life spans also increase and even a 100 year old, starts performing the chores of a 20-year-old.
PIMPLES:
Three tablespoons of honey and one teaspoon of cinnamon powder paste.
Apply this paste on the pimples before sleeping and wash it next morning with warm water. If done daily for two weeks, it removes pimples from the root
SKIN INFECTIONS:
Applying honey and cinnamon powder in equal parts on the affected parts cures eczema, ringworm and all types of skin infections.
WEIGHT LOSS:
Daily in the morning one half hour before breakfast on an empty stomach, and at night before sleeping, drink honey and cinnamon powder boiled in one cup of water.
If taken regularly, it reduces the weight of even the most obese person. Also, drinking this mixture regularly does not allow the fat to accumulate in the body even though the person may eat a high calorie diet.
CANCER:
Recent research in Japan and Australia has revealed that advanced cancer of the stomach and bones have been cured successfully.
Patients suffering from these kinds of cancer should daily take one tablespoon of honey with one teaspoon of cinnamon powder for one month three times a day.
FATIGUE:
Recent studies have shown that the sugar content of honey is more helpful rather than being detrimental to the strength of the body.
Senior citizens, who take honey and cinnamon powder in equal parts, are more alert and flexible.
Dr. Milton, who has done research, says that a half tablespoon of honey taken in a glass of water and sprinkled with cinnamon powder, taken daily after brushing and in the afternoon at about 3:00 P.M., when the vitality of the body starts to decrease, increases the vitality of the body within a week.
BAD BREATH:
People of South America , first thing in the morning, gargle with one teaspoon of honey and cinnamon powder mixed in hot water, so their breath stays fresh throughout the day.
HEARING LOSS:
Daily morning and night honey and cinnamon powder, taken in equal parts restores hearing.
